THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Silent mutation
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Non-sense mutation
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Deletion
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Missense mutation
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Detailed explanation-1: -This would change the UAU codon to UAG, a stop codon! The protein will end early; we call this a nonsense mutation.
Detailed explanation-2: -The last type of point mutation is called a nonsense mutation. And here you can see we have UAU, the original sequence that codes for tyrosine. If you replace the third U with an A you get UAA which is a stop codons. Stop codons do not code for an amino acid and they terminate translation.
Detailed explanation-3: -For example, if codon UAC, which normally codes for the amino acid tyrosine, mutates into UAG, a stop codon, the result is a nonsense mutation.
Detailed explanation-4: -Missense: A missense variant is a type of substitution in which the nucleotide change results in the replacement of one protein building block (amino acid) with another in the protein made from the gene. The amino acid change may alter the function of the protein.