THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Several codons (3-base sequences) can make the same amino acid
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The mutations are corrected before translation
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The reading frame is not affected
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Detailed explanation-1: -A silent mutation (quiet mutation) is a form of mutation that does not cause a major change in the amino acid. As a result, the protein remains active and functional. Because of this, the changes are viewed as though they are neutral in terms of evolution.
Detailed explanation-2: -Silent mutations occur when the change of a single DNA nucleotide within a protein-coding portion of a gene does not affect the sequence of amino acids that make up the gene’s protein.
Detailed explanation-3: -A change occurs in the third bases in most of the codon codes for the same amino acid. For example, the codon GUG codes for valine. If the third base is substituted with A, it codes for the same amino acid valine. Therefore, most of the changes in the third position lead to silent mutation.