THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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addition of one or more nucleic acids
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removal of one or more nucleic acids
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replacement of one or more nucleic acids
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frameshift ____ nucleic acids are separated from their original trio
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Detailed explanation-1: -A frameshift mutation is produced either by insertion or deletion of one or more new bases. Because the reading frame begins at the start site, any mRNA produced from a mutated DNA sequence will be read out of frame after the point of the insertion or deletion, yielding a nonsense protein.
Detailed explanation-2: -An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.
Detailed explanation-3: -Frameshift mutations Insertion or deletion of one or more nucleotides during replication can also lead to another type of mutation known as a frameshift mutation. The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein.
Detailed explanation-4: -In a chromosome deletion, the frame shift mutation will not occur if the number of bases is three. Because the bases are always read as triplet codons which has a set of three bases. If any one or two is missing, the reading of the codon, that is the frame for coding will cause frame shift mutation.