THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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No, all mutations lead to a different amino acid, therefore possibly resulting in a different protein
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Yes, some mutations can code for the same amino acids, in the same order and therefore cause no change to the protein
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Detailed explanation-1: -While mutations always change the DNA sequence, they do not always cause a change in the resulting protein or an obvious effect on the organism. This can occur because most amino acids can be coded by two or more different codons.
Detailed explanation-2: -Silent mutations occur when the change of a single DNA nucleotide within a protein-coding portion of a gene does not affect the sequence of amino acids that make up the gene’s protein.
Detailed explanation-3: -Types of Mutations Yet another type of mutation is the nonsynonymous mutation, in which an amino acid sequence is changed. Such mutations lead to either the production of a different protein or the premature termination of a protein.
Detailed explanation-4: -Mutations in a gene can result in a change in the sequence of amino acids such as in frameshift mutations and in missense and nonsense mutations occurring in point mutations. However, point mutations can also lead to silent mutations.
Detailed explanation-5: -For example, some variants alter a gene’s DNA sequence but do not change the function of the protein made from the gene. Often, gene variants that could cause a genetic disorder are repaired by certain enzymes before the gene is expressed and an altered protein is produced.