AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Name the mutation that happens when an extra base has been added to the sequence of bases.
A
Substitution
B
Deletion
C
Inversion
D
Insertion
Explanation: 

Detailed explanation-1: -A frameshift mutation in a gene refers to the insertion or deletion of nucleotide bases in numbers that are not multiples of three. This is important because a cell reads a gene’s code in groups of three bases when making a protein.

Detailed explanation-2: -Insertions and deletions An insertion mutation occurs when an extra nucleotide is added to the DNA strand during replication.

Detailed explanation-3: -An insertion changes the DNA sequence by adding one or more nucleotides to the gene. As a result, the protein made from the gene may not function properly.

Detailed explanation-4: -One type of frameshift mutation is called insertion. As the name implies, an insertion occurs when a single nitrogen base is accidentally added in the middle of a sequence. This throws off the reading frame of the DNA and the wrong amino acid is translated.

Detailed explanation-5: -Two major categories of mutations are germline mutations and somatic mutations. Germline mutations occur in gametes. These mutations are especially significant because they can be transmitted to offspring and every cell in the offspring will have the mutation. Somatic mutations occur in other cells of the body.

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