AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Occurs when the DNA change does not alter the amino acid sequence of the polypeptide.
A
Frameshift Mutation
B
Insertion
C
Missense mutation
D
Silent Mutation
Explanation: 

Detailed explanation-1: -A nucleotide change in the DNA that does not result in an amino acid change in the protein is called a “synonomous” or “silent” mutation (see Figure 3.3).

Detailed explanation-2: -Silent mutation: Some mutations that change DNA bases do not have any effect on the sequence of amino acids in the protein. These mutations are called silent mutations and they do not affect the structure or function of the protein because there is no effect on the amino acid sequence.

Detailed explanation-3: -A silent mutation is a change in the sequence of nucleotide bases which constitutes DNA, without a subsequent change in the amino acid or the function of the overall protein. Sometimes a single amino acid will change, but if it has the same properties as the amino acid it replaced, little to no change will happen.

Detailed explanation-4: -Silent mutations occur when the change of a single DNA nucleotide within a protein-coding portion of a gene does not affect the sequence of amino acids that make up the gene’s protein.

Detailed explanation-5: -Silent mutation: Silent mutations cause a change in the sequence of bases in a DNA molecule, but do not result in a change in the amino acid sequence of a protein (Figure 1).

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