THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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harmful
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beneficial
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neutral
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Detailed explanation-1: -Red blood cells are usually round and flexible, so they move easily through blood vessels. In sickle cell anemia, some red blood cells are shaped like sickles or crescent moons. These sickle cells also become rigid and sticky, which can slow or block blood flow.
Detailed explanation-2: -Mutations in the HBB gene cause sickle cell disease. The HBB gene provides instructions for making one part of hemoglobin.
Detailed explanation-3: -Normally, red blood cells are disc-shaped and flexible enough to move easily through the blood vessels. If you have sickle cell disease, your red blood cells are crescent-or “sickle”-shaped. These cells do not bend or move easily and can block blood flow to the rest of your body.
Detailed explanation-4: -People who have sickle cell disease inherit two faulty hemoglobin genes, called hemoglobin S-one from each parent. A person has sickle cell trait when the hemoglobin S gene is inherited from only one parent and a normal hemoglobin gene-hemoglobin A-is inherited from the other.
Detailed explanation-5: -An inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels, and do not last as long as normal red blood cells.