AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
THE BAT PAT THE CAT mutated to THE BAT ATT HEC AT. What type of mutation shows here?
A
Deletion
B
Insertion
C
Substitution
D
Inversion
Explanation: 

Detailed explanation-1: -It is a type of frameshift mutation characterized by the loss of one or more nucleotides from the segment of DNA. Example of deletion mutation is DiGeorge syndrome. DiGeorge syndrome is a disorder caused due to the deletion of a small segment of chromosome 22.

Detailed explanation-2: -Sequence analysis allows for the interrogation of all bases within a gene and is used routinely by clinical laboratories to detect point mutations and small insertions and deletions.

Detailed explanation-3: -Two frameshift mutations in the CFTR genes cause cystic fibrosis (one involves the insertion of two nucleotides, and the other involves the deletion of one nucleotide).

There is 1 question to complete.