THE MOLECULAR BASIS OF INHERITANCE
GENE MUTATION
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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deletion
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insertion
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substitution
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nonsense
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Detailed explanation-1: -Insertion Mutation Examples For example, some diseases caused by insertional mutations include: Fragile X Syndrome. Huntington’s Disease. Myotonic dystrophy.
Detailed explanation-2: -Hereditary mutations include cystic fibrosis, hemophilia, and sickle cell disease. Other mutations can happen on their own during a person’s life. These are called sporadic, spontaneous, or new mutations. They affect only some cells.
Detailed explanation-3: -In Summary: Major Types of Mutations Mutations can be of many types, such as substitution, deletion, insertion, and translocation.
Detailed explanation-4: -An insertion mutation occurs when an extra nucleotide is added to the DNA strand during replication. This can happen when the replicating strand “slips, ” or wrinkles, which allows the extra nucleotide to be incorporated (Figure 2). Strand slippage can also lead to deletion mutations.