AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

GENE MUTATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the most common DNA repair mechanism
A
Apoptosis
B
Nucleotide Excision Repair
C
Methyl Directed Mismatch Repair
D
Ames Test
Explanation: 

Detailed explanation-1: -Consequently, the various types of excision repair are the most important DNA repair mechanisms in both prokaryotic and eukaryotic cells. In excision repair, the damaged DNA is recognized and removed, either as free bases or as nucleotides.

Detailed explanation-2: -DNA polymerase proofreading is the first process for fixing nucleotide mistakes in DNA. As a result, (b) DNA polymerase proofreading is the proper option.

Detailed explanation-3: -The basic mechanism of excision repair involves: (1) damage recognition; (2) subunit assembly; (3) dual incisions that result in excision of the damage-containing oligomer; (4) resynthesis to fill in the gap; and (5) ligation to regenerate an intact molecule.

Detailed explanation-4: -There are three types of repair mechanisms: direct reversal of the damage, excision repair, and postreplication repair. Direct reversal repair is specific to the damage.

Detailed explanation-5: -There are two main mechanisms for repairing double strand breaks: homologous recombination and classical nonhomologous end joining. Homologous recombination involves the exchange of nucleotide sequences to repair damaged bases on both strands of DNA through the utilization of a sister chromatid.

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