AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

STRUCTURE OF NUCLEIC ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Nucleosomes are involved in
A
supercoiling of chromosomes
B
regulation of transcription
C
both of these
D
neither of these
Explanation: 

Detailed explanation-1: -The nucleosome thus serves not only as a general gene repressor, but also as a repressor of all transcription (genic, intragenic, and intergenic). The core nucleosome performs a fundamental regulatory role, apart from the histone “tails, ” which modulate gene activity.

Detailed explanation-2: -Each nucleosome is composed of DNA wound 1.65 times around eight histone proteins.

Detailed explanation-3: -A nucleosome is the basic repeating subunit of chromatin packaged inside the cell’s nucleus.

Detailed explanation-4: -Nucleosomes are the basic packing unit of DNA built from histone proteins around which DNA is coiled. They serve as a scaffold for formation of higher order chromatin structure as well as for a layer of regulatory control of gene expression.

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