AP BIOLOGY

Detailed explanation-1: -denaturation, in biology, process modifying the molecular structure of a protein. Denaturation involves the breaking of many of the weak linkages, or bonds (e.g., hydrogen bonds), within a protein molecule that are responsible for the highly ordered structure of the protein in its natural (native) state .

Detailed explanation-2: -During the denaturation of proteins, the secondary and tertiary structures get destroyed and only the primary structure is retained. Covalent bonds are broken and interaction between amino-acid chains gets disrupted. This results in the loss of biological activity of the proteins.

Detailed explanation-3: -The denatured protein has the same primary structure as the original, or native, protein. The weak forces between charged groups and the weaker forces of mutual attraction of nonpolar groups are disrupted at elevated temperatures, however; as a result, the tertiary structure of the protein is lost.

Detailed explanation-4: -Denaturation destroys the primary structure of the protein, and the protein breaks down to monomers. Different amino acids are substituted into the sequence, so the protein’s properties change. The protein’s pH changes, and the change causes the protein to lose its functionality.