AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

STRUCTURE OF NUCLEIC ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the distinction between short tandem repeats (STRs) and genes?
A
STRs have greater amounts of guanine
B
STRs have greater amounts of cytosine
C
STRs are not replicated
D
STRs are not transcribed
Explanation: 

Detailed explanation-1: -Short tandem repeats (STRs) are short repeated sequences of DNA (2–6 bp) that account for approximately 3% of the human genome (Lander et al., 2001). The number of repeat units is highly variable among individuals, which offers a high power of discrimination when analyzed for identification purposes.

Detailed explanation-2: -Specific pattern of transcription of tandemly repetitive DNA in chicken embryogenesis. In chicken, long non-coding MHM RNA formed by tandem repeats is transcribed from antisense strand on lampbrush chromosomes51 and also from both strands during female embryogenesis.

Detailed explanation-3: -VNTR and STR are two different types of tandem repeats found in a eukaryotic genome. The difference between the two lies in their base pairs. The repetitive unit of VNTR is 10-60 base pairs while that of STR is 2-6 base pairs.

Detailed explanation-4: -Short tandem repeats (STRs), or “microsatellites, ” are tracks of tandemly repeated short (1 to 6 bp) DNA sequence motifs. STRs may occur in both intergenic and intragenic regions, including within genes, and account for approximately 3% of the human genome.

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