AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

STRUCTURE OF NUCLEIC ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What principle is necessary to preserve the sequence of DNA during replication?
A
Base pairing is complementary.
B
One gene codes for one polypeptide.
C
Substrates are specific to enzymes.
D
The genetic code is universal.
Explanation: 

Detailed explanation-1: -Replication relies on complementary base pairing, that is the principle explained by Chargaff’s rules: adenine (A) always bonds with thymine (T) and cytosine (C) always bonds with guanine (G).

Detailed explanation-2: -Complementary base pairing is the phenomenon where in DNA guanine always hydrogen bonds to cytosine and adenine always binds to thymine. The bond between guanine and cytosine shares three hydrogen bonds compared to the A-T bond which always shares two hydrogen bonds.

Detailed explanation-3: -Bases pair up with each other in a consistent way, and this process is called complementary base pairing, or Watson-Crick base pairing. This consistent pairing of bases allows DNA to accurately replicate itself. It also allows DNA to be transcribed accurately into RNA and then translated from RNA to amino acids.

There is 1 question to complete.