THE MOLECULAR BASIS OF INHERITANCE
STRUCTURE OF NUCLEIC ACIDS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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25% A/T and 75% C/G
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50% A/T and 50% C/G
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75% A/T and 25% C/G
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100% A/T and 0% C/G
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Detailed explanation-1: -A DNA molecule consisting only of guanines and cytosines is much more stable and melts around or above 100°C depending on the concentration of NaCl.
Detailed explanation-2: -B-DNA is the most common type of DNA but not the most stable. A-DNA is the most stable despite it being rare.
Detailed explanation-3: -It is known that the stability of the double helical structure of B-DNA is supplied by the hydrogen bonds as proposed by Watson and Crick3 and by the stacking interactions.
Detailed explanation-4: -While DNA contains deoxyribose, RNA contains ribose, characterised by the presence of the 2′-hydroxyl group on the pentose ring (Figure 5). This hydroxyl group make RNA less stable than DNA because it is more susceptible to hydrolysis.