AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

STRUCTURE OF NUCLEIC ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following describes the role of DNA polymerase III?
A
Attaching complementary nucleotides together during replication
B
Attaching codons to anticodons
C
Attaching DNA nucleotides to the growing DNA strand during replication
D
Attaching amino acids to tRNA molecules
Explanation: 

Detailed explanation-1: -In prokaryotic cells, polymerase III is the major replicative polymerase, functioning in the synthesis both of the leading strand of DNA and of Okazaki fragments by the extension of RNA primers. Polymerase I then removes RNA primers and fills the gaps between Okazaki fragments.

Detailed explanation-2: -The main function of the third polymerase, Pol III, is duplication of the chromosomal DNA, while other DNA polymerases are involved mostly in DNA repair and translesion DNA synthesis. Together with a DNA helicase and a primase, Pol III HE participates in the replicative apparatus that acts at the replication fork.

Detailed explanation-3: -For example, DNA polymerase III does most of the elongation work, adding nucleotides one by one to the 3’ end of the new and growing single strand.

Detailed explanation-4: -Primase shows its working by creating an RNA primer. This primer is being utilized by DNA polymerase III for producing the daughter strands. Therefore, the correct answer is C.

Detailed explanation-5: -DNA polymerase III adds DNA nucleotides to the primer(s), synthesizing the DNA of both the leading and the lagging strands.

There is 1 question to complete.