THE MOLECULAR BASIS OF INHERITANCE
STRUCTURE OF NUCLEIC ACIDS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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DNA
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RNA
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amino acid
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chromosome
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Detailed explanation-1: -All nucleic acids contain the bases A, C, and G; T, however, is found only in DNA, while U is found in RNA. The pentose sugar in DNA (2′-deoxyribose) differs from the sugar in RNA (ribose) by the absence of a hydroxyl group (―OH) on the 2′ carbon of the sugar ring.
Detailed explanation-2: -Deoxyribonucleic acid (abbreviated DNA) is the molecule that carries genetic information for the development and functioning of an organism. DNA is made of two linked strands that wind around each other to resemble a twisted ladder-a shape known as a double helix.
Detailed explanation-3: -Amplification of DNA by the polymerase chain reaction is a much more sensitive technique for detecting cellular DNA or RNA sequences than is Southern or Northern blotting. Approximately 100, 000 copies of a DNA or RNA sequence are required for detection by blot hybridization.
Detailed explanation-4: -One of the techniques (Sanger’s method) resides in enzymatic synthesis of DNA copies (cDNAs) terminating at one of the four nucleotides; the other technique is based on chemical cleavage of DNA at one or only two of the four nucleotides (Maxam-Gilbert method).