AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

THE GENETICS OF VIRUSES AND BACTERIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A man with hemophilia (a recessive, sex linked condition) has a daughter of normal phenotype. She marries a man who is normal for the trait. If the couple has four sons, what is the probability that all four will be born with hemophilia?
A
1/2
B
1/4
C
1/8
D
1/16
Explanation: 

Detailed explanation-1: -So a carrier’s son has a 50% chance of having hemophilia. A baby girl will inherit an X chromosome with a dominant gene for normal blood clotting from her father. So the daughter will not have hemophilia.

Detailed explanation-2: -If a mother is heterozygous (a carrier) for hemophilia and the father does not have hemophilia, each son has a 1 in 2 (50%) chance of getting his mother’s hemophilia allele and having hemophilia. Each daughter has a 1 in 2 (50%) chance of getting her mother’s hemophilia allele and being heterozygous.

Detailed explanation-3: -As shown in the above diagram, the female offspring will not have hemophilia. However, there is a 50% chance that a female will be a carrier of the disorder. For a male offspring, there is a 50% chance that he will not inherit the disorder and a 50% that he will have hemophilia.

There is 1 question to complete.