THE MOLECULAR BASIS OF INHERITANCE
THE HUMAN GENOME
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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0%
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25%
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50%
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75%
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100%
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Detailed explanation-1: -If one parent has achondroplasia, the infant has a 50% chance of inheriting the disorder. If both parents have the condition, the infant’s chances of being affected increase to 75%.
Detailed explanation-2: -When both parents have achondroplasia, the chance for them, together, to have a child with normal stature is 25 percent. Their chance of having a child with achondroplasia is 50 percent.
Detailed explanation-3: -Achondroplasia is a form of dwarfism caused by a dominant allele. The homozygous dominant genotype causes death, so individuals who have this condition are all heterozygotes.
Detailed explanation-4: -Based on this study, the prevalence rate for achondroplasia was estimated to be 0.5-1.5 cases per 10, 000 births (1 in 20, 000 to 1 in 6, 666 births) and the mutation rate to be 1.72-5.57 x 10-5 per gamete per generation.