AP BIOLOGY

Detailed explanation-1: -Gene therapy is a technique that modifies a person’s genes to treat or cure disease. Gene therapies can work by several mechanisms: Replacing a disease-causing gene with a healthy copy of the gene. Inactivating a disease-causing gene that is not functioning properly.

Detailed explanation-2: -Gene Transfer: The introduction of new DNA into an existing organism’s cell, usually by vectors such as plasmids and modified viruses. Cells may be modified ex vivo for subsequent administration to humans, or may be altered in vivo by gene therapy given directly to the subject.

Detailed explanation-3: -Gene therapy techniques allow doctors to treat a disorder by altering a person’s genetic makeup instead of using drugs or surgery. The earliest method of gene therapy, often called gene transfer or gene addition, was developed to: Introduce a new gene into cells to help fight a disease.

Detailed explanation-4: -On September 14, 1990, W. French Anderson and his colleagues at the NIH performed the first approved gene therapy procedure on a four-year-old girl born with severe combined immunodeficiency (SCID) (Anderson, 1990).