AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

THE HUMAN GENOME

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The Human Genome Project allowed the first accurate estimates of the number of different genes in the human genome. What was a typical estimate, based on the results of the Human Genome Project?
A
46
B
64
C
25 000
D
1 000 000
Explanation: 

Detailed explanation-1: -"Dispute Over Number of Human Genes, ” BBC News Online.] When analysis of the draft human genome sequence was published by the International Human Genome Sequencing Consortium on February 15, 2001, the paper estimated only about 30, 000 to 40, 000 protein-coding genes, much lower than previous estimates of about 100, 000.

Detailed explanation-2: -A wealth of information is obtained from the initial analysis of the human genome draft. For instance, the number of human genes is originally estimated to be about 35, 000. (This is later revised to about 20, 000.) Researchers also report that the DNA sequences of any two human individuals are 99.9% identical.

Detailed explanation-3: -The Human Genome Project identified the full set of human genes, sequenced them all, and identified some of the alleles, particularly those that can cause disease when they get mutated. Genes can be mapped relative to physical features of the chromosome, or relative to other genes.

Detailed explanation-4: -The finished sequence produced by the Human Genome Project covers about 99 percent of the human genome’s gene-containing regions, and it has been sequenced to an accuracy of 99.99 percent.

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