AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

THE SEARCH FOR INHERITABLE MATERIAL

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The work of Erwin Chargaff allowed Watson and Crick to determine the rules of ____
A
protein synthesis
B
transcription
C
hydrogen bonding
D
nitrogen base pairing
Explanation: 

Detailed explanation-1: -Chargaff’s research would later help the Watson and Crick laboratory team to deduce the double helical structure of DNA. The second of Chargaff’s rules is that the composition of DNA varies from one species to another, in particular in the relative amounts of A, G, T, and C bases.

Detailed explanation-2: -Chargaff’s Rule showed that in natural DNA, the number of guanine units equals the number of cytosine units and the number of adenine units equals the number of thymine units. This strongly hinted towards the base pair makeup of the DNA.

Detailed explanation-3: -In Watson and Crick’s model, the two strands of the DNA double helix are held together by hydrogen bonds between nitrogenous bases on opposite strands. Each pair of bases lies flat, forming a “rung” on the ladder of the DNA molecule. Base pairs aren’t made up of just any combination of bases.

Detailed explanation-4: -Chargaff’s rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine.

There is 1 question to complete.