AP BIOLOGY

Detailed explanation-1: -Classic CJD is a human prion disease. It is a neurodegenerative disorder with characteristic clinical and diagnostic features. This disease is rapidly progressive and always fatal. Infection with this disease leads to death usually within 1 year of onset of illness.

Detailed explanation-2: -CJD is classified as a transmissible spongiform encephalopathy (TSE) along with other prion diseases that occur in humans and animals. In about 85% of patients, CJD occurs as a sporadic disease with no recognizable pattern of transmission.

Detailed explanation-3: -Creutzfeldt-Jakob disease (CJD) is caused by an abnormal infectious protein in the brain called a prion. Proteins are molecules made up of amino acids that help the cells in our body function.

Detailed explanation-4: -Variant Creutzfeldt-Jakob disease is a rare and fatal neurodegenerative brain disorder believed to be acquired through the consumption of beef products made from cattle infected with bovine spongiform encephalopathy (BSE), an animal prion disease commonly referred to as “mad cow” disease.

Detailed explanation-5: -Mad cow disease, or bovine spongiform encephalopathy (BSE), is a disease that was first found in cattle. It’s related to a disease in humans called variant Creutzfeldt-Jakob disease (vCJD).