AP BIOLOGY

THE MOLECULAR BASIS OF INHERITANCE

VIRUSES AND PRIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Infectious particles that cause neurodegenerative diseases such as Kuru and mad cow disease are called
A
viroids
B
virusoid
C
prions
D
retrroviruses
Explanation: 

Detailed explanation-1: -BSE also known as Mad Cow Disease is a progressive neurological disorder of cattle that results from infection by an unusual transmissible agent called a prion.

Detailed explanation-2: -Kuru. This disease is seen in New Guinea. It’s caused by eating human brain tissue contaminated with infectious prions. Because of increased awareness about the disease and how it is transmitted, kuru is now rare.

Detailed explanation-3: -Creutzfeldt-Jakob disease (CJD) is a rapidly progressive, invariably fatal neurodegenerative disorder believed to be caused by an abnormal isoform of a cellular glycoprotein known as the prion protein.

Detailed explanation-4: -Familial Creutzfeldt–Jakob disease, Gerstmann–Sträussler–Scheinker disease, and fatal familial insomnia are all dominantly inherited prion diseases caused by mutations in the prion protein gene (PRNP) (Table 2).

Detailed explanation-5: -Bovine Spongiform Encephalopathy (BSE), or Mad Cow Disease Currently, the most accepted theory is that the agent is a modified form of a normal protein known as prion protein.

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