AP BIOLOGY

BIOCHEMISTRY

ENZYMES AND METABOLISM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
At temperatures above 40-45 degrees, proteins ____
A
create so many products that body processes go too fast and the body overheats
B
grow bigger and acquire more amino acids
C
denature and no longer function
D
slow down metabolism but keep functioning
Explanation: 

Detailed explanation-1: -Because enzymes are proteins, they are denatured by heat. Therefore, at higher temperatures (over about 55°C in the graph below) there is a rapid loss of activity as the protein suffers irreversible denaturation.

Detailed explanation-2: -Because most animal enzymes rapidly become denatured at temperatures above 40°C, most enzyme determinations are carried out somewhat below that temperature. Over a period of time, enzymes will be deactivated at even moderate temperatures. Storage of enzymes at 5°C or below is generally the most suitable.

Detailed explanation-3: -As with many chemical reactions, the rate of an enzyme-catalysed reaction increases as the temperature increases. However, at high temperatures the rate decreases again because the enzyme becomes denatured and can no longer function.

Detailed explanation-4: -As with increases in temperature, extreme acidity or basicity can interrupt the molecular bonds holding an enzyme together. The loss of these intra-and inter-molecular interactions causes enzymes to lose their shape, resulting in denatured enzymes that are no longer functional.

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