BIOCHEMISTRY
ENZYMES AND METABOLISM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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binds with the allosteric site
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binds with the substrate
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binds with allosteric inhibitors
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is inhibited by a coenzyme or a cofactor
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Detailed explanation-1: -The part of the enzyme where the substrate binds is called the active site (since that’s where the catalytic “action” happens). A substrate enters the active site of the enzyme. This forms the enzyme-substrate complex.
Detailed explanation-2: -Inhibitor binds to the active site of enzyme in inhibition while it binds to allosteric site of an enzyme in inhibition.
Detailed explanation-3: -The active site is a groove or crevice on an enzyme in which a substrate binds to facilitate the catalyzed chemical reaction. Enzymes are typically specific because the conformation of amino acids in the active site stabilizes the specific binding of the substrate.
Detailed explanation-4: -Substrate bind to the active site of the enzyme through a variety of interactions. These forces are van der Waal, interactions, ionic bonding, hydrogen bonding or dipole-dipole interaction.