BIOCHEMISTRY
ENZYMES AND METABOLISM
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Iron
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Mercury
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Penicillin
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Vitamin B
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Detailed explanation-1: -Enzymes inhibited by mercury include acetylcholinesterase, catalase, dipeptyl peptidase (CD26), amylase, lipase, lactase and glucose-6-phosphatase.
Detailed explanation-2: -Mercury and other toxic heavy metals disrupt cellular function by inhibiting or denaturing critical enzymes and proteins.
Detailed explanation-3: -Mercury, as mercuric ion, appears to be a reversible competitive inhibitor, which shows no distinct dependence upon pH or counter-ion concentration and does not completely inacti-vate the enzyme (Myrback, 1957).
Detailed explanation-4: -Examples of enzyme-inhibiting agents are cimetidine, erythromycin, ciprofloxacin, and isoniazid.
Detailed explanation-5: -They are competitive inhibition, non-competitive inhibition, uncompetitive inhibition, and mixed inhibition.