AP BIOLOGY

Detailed explanation-1: -Metaphase. Chromosomes line up at the metaphase plate, under tension from the mitotic spindle. The two sister chromatids of each chromosome are captured by microtubules from opposite spindle poles. In metaphase, the spindle has captured all the chromosomes and lined them up at the middle of the cell, ready to divide.

Detailed explanation-2: -Metaphase: During metaphase, each of the 46 chromosomes line up along the center of the cell at the metaphase plate.

Detailed explanation-3: -During metaphase, spindle fibers attach to the centromere of each pair of sister chromatids (see Figure below). The sister chromatids line up at the equator, or center, of the cell. This is also known as the metaphase plate.

Detailed explanation-4: -During metaphase, the microtubules pull the sister chromatids back and forth until they align in a plane, called the equatorial plane, along the center of the cell. During anaphase, the sister chromatids are separated simultaneously at their centromeres.

Detailed explanation-5: -During metaphase I, all of the doubled homologous chromosome pairs line up along the midline of the cell between the two centrioles. During anaphase I, the homologous chromosome pairs separate and are pulled to opposite poles of the cell by spindle fibers attached to the centrioles.