AP BIOLOGY

CELL DIVISION

MEIOSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Nondisjunction during meiosis results in an abnormal number of chromosomes in one or more gametes. In some cases of nondisjunction, a single chromosome fails to separate. In others, none of the chromosomes separate. Suppose an egg is produced in which none of the chromosomes separate during meiosis II. What is the chromosomes number of the zygote that results if this egg is fertilized by a normal sperm?
A
1n
B
2n
C
2n+1
D
3n
Explanation: 

Detailed explanation-1: -Nondisjunction in meiosis II results from the failure of the sister chromatids to separate during anaphase II. Since meiosis I proceeded without error, 2 of the 4 daughter cells will have a normal complement of 23 chromosomes. The other 2 daughter cells will be aneuploid, one with n+1 and the other with n-1.

Detailed explanation-2: -Nondisjunction in meiosis can result in pregnancy loss or birth of a child with an extra chromosome in all cells, whereas nondisjunction in mitosis will result in mosaicism with two or more cell lines. Aneuploidy may also result from anaphase lag.

Detailed explanation-3: -Disorders of chromosome number include the duplication or loss of entire chromosomes, as well as changes in the number of complete sets of chromosomes. They are caused by nondisjunction, which occurs when pairs of homologous chromosomes or sister chromatids fail to separate during meiosis.

Detailed explanation-4: -Nondisjunction is the failure of homologous chromosomes to disjoin correctly during meiosis. This results in the production of gametes containing a greater or lesser chromosomal amount than normal ones. Consequently the individual may develop a trisomal or monosomal syndrome.

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