AP BIOLOGY

Detailed explanation-1: -During prophase, the chromosomes condense, the nucleolus disappears, and the nuclear envelope breaks down.

Detailed explanation-2: -Meiosis I, the first meiotic division, begins with prophase I. During prophase I, the complex of DNA and protein known as chromatin condenses to form chromosomes. The pairs of replicated chromosomes are known as sister chromatids, and they remain joined at a central point called the centromere.

Detailed explanation-3: -Nuclear membrane starts disappearing at the start of mitosis and by the late prophase it disappears completely along with the major cell organelles. The nuclear membrane disappears presumably to allow more space for karyokinesis and proper separation of chromatids.

Detailed explanation-4: -At the end of prophase I, the nuclear membrane breaks down, the centrosomes have migrated to the opposite ends of the cell, and the spindle apparatus is being formed. This is followed by metaphase I. During this stage, the spindle fibers, or microtubules, attach to the centromere of each chromosome.

Detailed explanation-5: -After prophase is complete, the cell enters prometaphase. During prometaphase, the nuclear membrane disintegrates and the mitotic spindle gains access to the chromosomes. During this phase, a protein structure called the kinetochore is associated with the centromere on each sister chromatid.