AP BIOLOGY

Detailed explanation-1: -Cancer is a disease caused when cells divide uncontrollably and spread into surrounding tissues. Cancer is caused by changes to DNA. Most cancer-causing DNA changes occur in sections of DNA called genes. These changes are also called genetic changes.

Detailed explanation-2: -Disruption of normal regulation of the cell cycle can lead to diseases such as cancer. When the cell cycle proceeds without control, cells can divide without order and accumulate genetic errors that can lead to a cancerous tumor .

Detailed explanation-3: -Cancer is a disease in which some of the body’s cells grow uncontrollably. There are many different types of cancer, and each begins when a single cell acquires a genomic change (or mutation) that allows the cell to divide and multiply unchecked. Additional mutations can cause the cancer to spread to other sites.

Detailed explanation-4: -Cancers, however, occur due to an alteration of a normal biological process-cell division. Cells that progress through the cell cycle unchecked may eventually form malignant tumors, where masses of cells grow and divide uncontrollably, then develop the ability to spread and migrate throughout the body.

Detailed explanation-5: -Cancer is essentially a disease of mitosis-the normal ‘checkpoints’ regulating mitosis are ignored or overridden by the cancer cell. Cancer begins when a single cell is transformed, or converted from a normal cell to a cancer cell.