AP BIOLOGY

Detailed explanation-1: -Glucose-6-phosphate isomerase (GPI), the second enzyme in the glycolytic pathway, is a dimeric enzyme that catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate. This enzyme has been linked to the proliferation and motility of cancer cells via its control over glucose-6-phosphate levels [72].

Detailed explanation-2: -Glucose-6-phosphate (G6P) is changed into fructose-6-phosphate (F6P) by phosphoglucoisomerase (phosphoglucose isomerase) in the second step.

Detailed explanation-3: -The second step of glycolysis involves the conversion of glucose-6-phosphate to fructose-6-phosphate (F6P). This reaction occurs with the help of the enzyme phosphoglucose isomerase (PI). As the name of the enzyme suggests, this reaction involves an isomerization reaction.

Detailed explanation-4: -Phosphofructokinase catalyzes the conversion of fructose-6-phosphate to fructose-1, 6-diphosphate and is a key regulatory enzyme of glycolysis.