AP BIOLOGY

Detailed explanation-1: -Cyanide is a poison that inhibits the electron transport chain by creating a strong and stable bond with Fe-Cu center in cytochrome C oxidase (complex IV). What is the immediate consequence cyanide poisoning? Prevent reduction of oxygen.

Detailed explanation-2: -Cyanide binds to Fe3+ in heme-containing proteins. This inhibits the terminal cytochrome complex IV of the electron transport chain. The blocklock of complex IV by cyanide depletes ATP culminating in cell death. Oxygen is unable to reoxidize the reduced cytochrome a3.

Detailed explanation-3: -The cyanide ion, CN, binds to the iron atom in cytochrome C oxidase in the mitochondria of the cells and acts as an irreversible enzyme inhibitor. This prevents cytochrome C oxidase from doing what it needs to do, which is to send electrons to oxygen in the electron transport chain of aerobic cellular respiration.

Detailed explanation-4: -Cyanide reversibly binds to the ferric ions cytochrome oxidase three within the mitochondria. This effectively halts cellular respiration by blocking the reduction of oxygen to water.

Detailed explanation-5: -Cyanide: inhibits terminal electron transfer to oxygen, Complex IV.