AP BIOLOGY

CELL RESPIRATION

THE KREBS CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What does acetyl-CoA combine with to produce citric acid?
A
4-carbon compound
B
2-carbon compound
C
pyruvic acid
D
NAD+
Explanation: 

Detailed explanation-1: -First, acetyl CoA combines with oxaloacetate, a four-carbon molecule, losing the CoA group and forming the six-carbon molecule citrate. After citrate undergoes a rearrangement step, it undergoes an oxidation reaction, transferring electrons to NAD+ to form NADH and releasing a molecule of carbon dioxide.

Detailed explanation-2: -To start the cycle, an enzyme fuses acetyl CoA and oxaloacetate together so that citric acid is formed (a 2-carbon molecule + a 4-carbon molecule = a 6-carbon molecule!). This is the first molecule that is made in the cycle and is where the cycle gets its name.

Detailed explanation-3: -The Krebs cycle itself actually begins when acetyl-CoA combines with a four-carbon molecule called OAA (oxaloacetate) (see Figure above). This produces citric acid, which has six carbonatoms.

Detailed explanation-4: -Each Acetyl CoA consists of 2 carbon atoms.

There is 1 question to complete.