AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A strand of DNA in a skin cell contains the bases:A-T-G-C-C-A-T-C-G-G-T-AAfter the cell is exposed to ultraviolet light, the strand contains the bases:A-T-G-G-C-C-A-T-C-G-G-T-A
A
There have been no changes in the bases.
B
One base has been substituted for another.
C
A base has been deleted
D
A new base has been inserted.
Explanation: 

Detailed explanation-1: -UV radiation induces two of the most abundant mutagenic and cytotoxic DNA lesions such as cyclobutane-pyrimidine dimers (CPDs) and 6-4 photoproducts (6-4PPs) and their Dewar valence Isomers.

Detailed explanation-2: -The exposure of UVR, IR, and certain genotoxic chemicals may result in single as well as double DNA strand breaks. Among different types of damages, DNA double strand breaks (DSBs) are the most deleterious, since they affect both strands of DNA and can lead to the loss of genetic material.

Detailed explanation-3: -Unprotected exposure to UVA and UVB damages the DNA in skin cells, producing genetic defects, or mutations, that can lead to skin cancer and premature aging. UV rays can also cause eye damage, including cataracts and eyelid cancers.

Detailed explanation-4: -Your skin makes vitamin D naturally when it is exposed to UV rays from the sun. How much vitamin D you make depends on many things, including how old you are, how dark your skin is, and how strong the sunlight is where you live. Vitamin D has many health benefits. It might even help lower the risk of some cancers.

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