AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Among this list select the disorders that are caused by nondisjunction:(There are three)
A
Crit-du-chat syndrome
B
Down’s syndrome
C
Klinefelter’s syndrome
D
Turners syndrome
E
lymphoma
Explanation: 

Detailed explanation-1: -There are three forms of nondisjunction: failure of a pair of homologous chromosomes to separate in meiosis I, failure of sister chromatids to separate during meiosis II, and failure of sister chromatids to separate during mitosis. Nondisjunction results in daughter cells with abnormal chromosome numbers (aneuploidy).

Detailed explanation-2: -Turner syndrome (TS) is a complex phenotype associated with complete or partial monosomy of the X chromosome, usually the result of a sporadic chromosomal nondisjunction.

Detailed explanation-3: -Turner syndrome can increase the risk of an underactive thyroid (hypothyroidism) due to the autoimmune disorder Hashimoto’s thyroiditis. There is also an increased risk of diabetes. Sometimes Turner syndrome is associated with gluten intolerance (celiac disease) or inflammatory bowel disease.

There is 1 question to complete.