AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In a point mutation, this would have the worst effect on the function of the protein
A
an insertion or deletion near the end of a gene
B
an insertion or deletion at the beginning of the gene
C
an insertion at the middle of the gene
D
a base substitution
Explanation: 

Detailed explanation-1: -Answer and Explanation: (e) Insertion of one nucleotide is most likely to drastically affect a protein’s sequence. Insertion/deletion of any number of nucleotide/s (except in the multiple of three) will result in the mutation refer to as a frame-shift mutation.

Detailed explanation-2: -An insertion changes the DNA sequence by adding one or more nucleotides to the gene. As a result, the protein made from the gene may not function properly. A deletion changes the DNA sequence by removing at least one nucleotide in a gene.

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