AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Inversion mutations are when ____
A
A single N-base is changed.
B
A single N-base is added.
C
Part of a chromosomes is flipped/backwards.
D
Part of a chromosome break off and attaches to a new location.
Explanation: 

Detailed explanation-1: -An inversion occurs when a chromosome breaks in two places; the resulting piece of DNA is reversed and re-inserted into the chromosome. Genetic material may or may not be lost as a result of the chromosome breaks.

Detailed explanation-2: -Definition. An inversion in a chromosome occurs when a segment breaks off and reattaches within the same chromosome, but in reverse orientation. DNA may or may not be lost in the process.

Detailed explanation-3: -Inversion events can produce hybrid genes that have varying portions of two genes, not necessarily half and half. However, inversion events can connect half of a gene with a region of DNA that has no genes. The result would be a broken gene.

Detailed explanation-4: -Pericentric inversions are most frequent, often reported for chromosomes 1, 2, 3, 5, 9, 10 and 16. These are some of the most common cytogenetically visible rearrangements in humans-for example, the pericentric inversion of chromosome 9 is found in over 1% of karyotypes [17].

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