HEREDITY
MUTATIONS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Part of the chromosome is missing
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Part of the chromosome is attached backwards
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Part of the chromosome breaks off and attaches to a different chromosome
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Part of a chromosome is duplicated
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Detailed explanation-1: -An inversion occurs when a chromosome breaks in two places; the resulting piece of DNA is reversed and re-inserted into the chromosome. Genetic material may or may not be lost as a result of the chromosome breaks.
Detailed explanation-2: -An inversion occurs when a chromosome breaks at two points and the segment bounded by the breakpoints is reinserted in the reversed orientation.
Detailed explanation-3: -One of the best-characterized recurrent inversions giving rise to disease causes hemophilia A, an X-linked disorder caused by mutations in the factor VIII gene [36]. A recurrent inversion has been found in approximately 43% of patients [37].
Detailed explanation-4: -What happens in an inversion? Sometimes a chromosome breaks in two places and the broken piece rejoins the same chromosome, but upside down. This is called a chromosome inversion.
Detailed explanation-5: -Inversion events can produce hybrid genes that have varying portions of two genes, not necessarily half and half. However, inversion events can connect half of a gene with a region of DNA that has no genes. The result would be a broken gene.