AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
When a portion of a chromosomes breaks off, flips around backwards and reattaches this is called a(n)
A
deletion mutation
B
translocation mutation
C
inversion mutation
Explanation: 

Detailed explanation-1: -An inversion occurs when a chromosome breaks in two places; the resulting piece of DNA is reversed and re-inserted into the chromosome. Genetic material may or may not be lost as a result of the chromosome breaks.

Detailed explanation-2: -(in-VER-zhun) A chromosomal defect in which a segment of the chromosome breaks off and reattaches in the reverse direction.

Detailed explanation-3: -One well known example of an inversion mutation in humans is hemophilia, a disease that inhibits the ability of blood to clot. Researchers discovered the gene responsible for hemophilia years ago, but also found that DNA from a person with hemophilia had the same genetic makeup as a person without the disease.

Detailed explanation-4: -Chromosomal translocation refers to the transfer of chromosomal part to another chromosome, while genetic inversion takes place when a chromosomal part breaks off, rotates 180 degrees, and reattaches to the same chromosome.

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