HEREDITY
MUTATIONS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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They shift the the way the genetic message is read.
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They can change everything about the protein that is produced.
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Insertions, deletions, and substitutions are all types of frameshift mutations.
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Detailed explanation-1: -Which of the following are true of frameshift mutations? They are often much more severe than point mutations. They are caused by extra or missing nucleotides in a DNA sequence. A nonfunctional protein may be produced.
Detailed explanation-2: -Frameshift Mutation If a mutation disrupts this normal reading frame, then the entire gene sequence following the mutation will be incorrectly read. This can result in the addition of the wrong amino acids to the protein and/or the creation of a codon that stops the protein from growing longer.
Detailed explanation-3: -Due to the triplet nature of codons, the amino acid sequence of a protein is determined by contiguous triplets. Therefore, a frameshift mutation leads to completely different proteins in term of chemical composition, and the closer to 5′ end of coding sequence the mutation occurs, the more protein changes it can make.
Detailed explanation-4: -A single nucleotide base change, insertion or deletion of the genetic material causes frameshift mutation.