AP BIOLOGY

Detailed explanation-1: -Metaphase leads to anaphase, during which each chromosome’s sister chromatids separate and move to opposite poles of the cell.

Detailed explanation-2: -Anaphase: During anaphase, the centromere splits, allowing the sister chromatids to separate. The kinetochore spindle fibers shorten, allowing for 46 of the newly-freed chromatids to be dragged to one end of the cell and the remaining 46 chromatids to be dragged to the opposite end of the cell.

Detailed explanation-3: -Sister chromatids separate during anaphase in a three-stage program as directed by interaxis bridges.

Detailed explanation-4: -In anaphase, the sister chromatids separate from each other and are pulled towards opposite ends of the cell. The protein “glue” that holds the sister chromatids together is broken down, allowing them to separate. Each is now its own chromosome. The chromosomes of each pair are pulled towards opposite ends of the cell.

Detailed explanation-5: -During anaphase, each pair of chromosomes is separated into two identical, independent chromosomes. The chromosomes are separated by a structure called the mitotic spindle.