AP BIOLOGY

LABORATORY REVIEW

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In replication, DNA ____ “unzips” the DNA molecule
A
polymerase
B
phages
C
helicase
D
bonds
Explanation: 

Detailed explanation-1: -During DNA replication, DNA helicases unwind DNA at positions called origins where synthesis will be initiated. DNA helicase continues to unwind the DNA forming a structure called the replication fork, which is named for the forked appearance of the two strands of DNA as they are unzipped apart.

Detailed explanation-2: -DNA helicases catalyze the disruption of the hydrogen bonds that hold the two strands of double-stranded DNA together. This energy-requiring unwinding reaction results in the formation of the single-stranded DNA required as a template or reaction intermediate in DNA replication, repair and recombination.

Detailed explanation-3: -DNA replication occurs through the help of several enzymes. These enzymes “unzip” DNA molecules by breaking the hydrogen bonds that hold the two strands together. Each strand then serves as a template for a new complementary strand to be created.

Detailed explanation-4: -This separated, independent structure with all base pairs unzipped is called ssDNA. The DNA unzipping and the DNA unwinding result in a structural transformation from dsDNA to ssDNA.

Detailed explanation-5: -The enzyme helicase unzips the two strands of the double helix. Once unzipped, single stranded binding (SSB) proteins stabilize the newly single strands. The enzyme DNA gyrase ensure the double stranded areas beyond the replication fork do not supercoil onto one another.

There is 1 question to complete.