AP BIOLOGY

Detailed explanation-1: -The combination formed by an enzyme and its substrates is called the enzyme–substrate complex.

Detailed explanation-2: -As the temperature and therefore kinetic energy of the molecules increases, the enzymes and substrates will collide more often which results in an increased chance of a successful collision between the enzymes active site and the substrate.

Detailed explanation-3: -Catalysis happens in the following stages: The substrate binds to the enzyme’s active site, forming an enzyme-substrate complex (ES complex). The enzyme converts the substrate into product, forming an enzyme-product complex (EP complex).

Detailed explanation-4: -More collisions increase the likelihood that substrate will collide with the active site of the enzyme, thus increasing the rate of an enzyme-catalyzed reaction. Above a certain temperature, activity begins to decline because the enzyme begins to denature.