LABORATORY REVIEW
MOLECULAR BIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Start codon
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Promoter
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Terminator
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Initiation
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Detailed explanation-1: -Definition. A promoter, as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and transcription factors) bind to initiate transcription of that gene.
Detailed explanation-2: -Transcription factors recognize and bind to specific DNA sequences called promotor or enhancer sequences. Promotor sequences are typically upstream of a gene and ensure accurate initiation of transcription.
Detailed explanation-3: -Many eukaryotic genes have a conserved promoter sequence called the TATA box, located 25 to 35 base pairs upstream of the transcription start site. Transcription factors bind to the TATA box and initiate the formation of the RNA polymerase transcription complex, which promotes transcription.
Detailed explanation-4: -Transcription of a gene takes place in three stages: initiation, elongation, and termination.