THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Each cell has a different response to the ligand.
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Each cell has different receptors to bind to the ligand
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Each cell has different relay molecules based on the ligand.
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Each cell has different processes for endocytosis.
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Detailed explanation-1: -Cell-surface receptors come in three main types: ion channel receptors, GPCRs, and enzyme-linked receptors. When a ligand binds an ion channel receptor, a channel through the plasma membrane opens that allows specific ions to pass through. This process requires a specialized membrane-spanning region of the receptor.
Detailed explanation-2: -The same ligand can cause different responses in different cell types due to differences in protein expression in the different cells, where the same signal activates different signaling pathways, leading to a different response in each cell type.
Detailed explanation-3: -These assemblies, called multi-specific ligands, contain multiple receptor binding sites and are able to target different cell surface receptors simultaneously.
Detailed explanation-4: -The time a ligand spends attached to a receptor or specific protein is a function of the affinity between the ligand and the protein. The higher the affinity, the stronger the ligand will bind to the protein, and the longer the functional modification with last.
Detailed explanation-5: -In a common view of receptor signaling, specificity is encoded in the strength of ligand-receptor binding resulting from the details of molecular ligand-receptor interactions (1). A high affinity ligand typically produces a stronger response while a weak affinity ligand produces little response.