THE CELL
CELL COMMUNICATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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must be the right shape to have the ligand attach to it
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are often found freely floating in the bloodstream
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are typically made from phospholipids
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A and C
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Detailed explanation-1: -Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the ligand-binding site. The specificity of a protein’s ligand-binding site is determined by the arrangement of its amino acid chain which gives the area its shape and chemical reactivity.
Detailed explanation-2: -The time a ligand spends attached to a receptor or specific protein is a function of the affinity between the ligand and the protein. The higher the affinity, the stronger the ligand will bind to the protein, and the longer the functional modification with last.
Detailed explanation-3: -This increased affinity for the ligand causes a sigmoidal-or S-shaped-binding curve, as seen below. The sigmoidal curve shows a rapid increase in affinity and binding after the first and second ligands bind to their sites. This produces a sharp curve upward, forming an S shape.
Detailed explanation-4: -In biochemistry and molecular biology, a binding site is a region on a macromolecule such as a protein that binds to another molecule with specificity. The binding partner of the macromolecule is often referred to as a ligand.