AP BIOLOGY

THE CELL

CELL COMMUNICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is a phosphorylation cascade?
A
travelling of hormones through the blood
B
facilitated diffusion of hydrophilic molecules through a channel protein
C
the removal of a phosphate from a molecule
D
a series of molecules that are sequentially phosphorylated
Explanation: 

Detailed explanation-1: -A phosphorylation cascade is a sequence of signaling pathway events where one enzyme phosphorylates another, causing a chain reaction leading to the phosphorylation of thousands of proteins. This can be seen in signal transduction of hormone messages.

Detailed explanation-2: -Protein kinases The protein kinases belong to the great family of kinases and are responsible for the mechanism of phosphorylation. They are activated by phosphorylation which in turn activates a cascade of events leading to the phosphorylation of different amino acids (3).

Detailed explanation-3: -Steps 4, 5, and 7 include phosphorylation.

Detailed explanation-4: -Phosphorylation cascades involving a series of protein kinases are useful for cellular signal transduction because the number of molecules used is small and fixed. they counter the harmful effects of phosphatases.

Detailed explanation-5: -In the phosphorylation cascade, protein kinase activates protein by adding a phosphate group, whereas protein phosphatase removes the phosphate group by inactivating them. Thus, these two enzymes regulate the activities of protein in response to a signaling molecule.

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