THE CELL
CELL COMMUNICATION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
MPF
|
|
|
protein kinase
|
|
|
cyclin
|
|
|
cdk
|
Detailed explanation-1: -1. The protein that is maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active is CDK. Explanation: CDK stands for cyclin-dependent kinase.
Detailed explanation-2: -In general, Cdk levels remain relatively constant across the cell cycle, but Cdk activity and target proteins change as levels of the various cyclins rise and fall.
Detailed explanation-3: -Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active? cyclins.
Detailed explanation-4: -Cyclin A/CDK2 terminates the S phase by phosphorylating CDC6 and E2F1; it drives the cell-cycle transition from S phase to G2 phase, and subsequently activates CDK1 by cyclin A, leading to cells entering the M phase. Upon mitosis, the CDK1 activity is maintained by the complex cyclin B/CDK1.
Detailed explanation-5: -What must happen for a Cdk to be active? It must bind to its cyclin partner.