AP BIOLOGY

Detailed explanation-1: -A secondary immune deficiency disease occurs when the immune system is compromised due to an environmental factor. Examples of these outside forces include HIV, chemotherapy, severe burns or malnutrition.

Detailed explanation-2: -Perhaps the most well known secondary immunodeficiency is caused by HIV infection; however, the most prevalent cause of immunodeficiency worldwide is severe malnutrition, which affects as much as 50% of the population in some impoverished communities.

Detailed explanation-3: -Secondary Immunodeficiency Secondary immunodeficiencies can be caused by: Systemic disorders such as diabetes mellitus, malnutrition, hepatitis, or HIV infection. Immunosuppressive treatments such as cytotoxic chemotherapy, bone marrow ablation before transplantation, or radiation therapy.

Detailed explanation-4: -Secondary immunodeficiencies, also known as acquired immunodeficiencies, can result from various immunosuppressive agents, for example, malnutrition, aging and particular medications (e.g., chemotherapy, disease-modifying antirheumatic drugs, immunosuppressive drugs after organ transplants, glucocorticoids).